LitGENE is an interpretable transformer-based model that integrates textual information and gene ontologies through contrastive learning to refine gene representations. The approach combines gene annotation with gene description to predict gene functions and attributes. This is achieved by integrating contrastive learning within a large language model.
Figure 1: Overview of LitGENE Model
The website accepts descriptions of biomedical entities, such as genes/proteins, pathways, diseases, or drugs. Researchers and clinicians can input scientific abstracts (in prompt window) related to these entities and receive predictions of related biological entities.
LitGENE provides predictions of biomedical entities related to the input prompt.
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